New Potent Cannabinoids Have Been Discovered

It seems that every day we are learning more and more about the cannabis plant, even though it has already been around for our entire lifetime. One of the latest discoveries comes out of Italy, where local researchers believe they’ve found two new cannabinoids. 

Their article published in December 2019, shows their discovery of -and the properties of the- new cannabinoids THCP and CBDP. As seen by their names, they are very similar to the structure of the commonly known THC and CBD cannabinoids. However, it is believed that they may be up to thirty times more potent!

Let’s Compare

THCP & THC

The researchers tested the THCP (tetrahydrocannabiphorol) cannabinoid on mice. They stated that the compound exhibited very similar effects as THC, but at higher levels. As the potency levels were quite clearly observed in mice, it is yet to be seen how it will act in humans. 

In their report, the researchers did express their expectation that THCP has a higher affinity to bind to CB1 receptors in our brains and a greater effect than THC itself. Let’s hope!

CBDP & CBD

This compound, as evident in the name, is very similar to what we know as CBD. CBDP (cannabidiphorol), as opposed to CBD, is relatively unknown and requires a lot more research. From what we do know, CBD is not all that effective in binding to relative receptors in our brains. 

This means it is quite possible that CBDP has the potential to be stronger in binding to these receptors and better at interacting with the endocannabinoid system (ECS). So it would seem that this cannabinoid will produce similar effects to CBD, but be a lot more effective in what it does thanks to stronger binding to receptors and impact on the ECS. 

With these discoveries, it could elevate the medical potential of cannabis. It also goes to show how much of this plant may still be waiting to be discovered and unlocked. For now, we will keep an eye on this development, and see what comes of these newly discovered cannabinoids.